Practical syntheses of N-substituted 3-hydroxyazetidines and 4-hydroxypiperidines by hydroxylation with Sphingomonas sp. HXN-200

D Chang, HJ Feiten, KH Engesser, JB van Beilen…

Index: Organic Letters, , vol. 4, # 11 p. 1859 - 1862

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Citation Number: 46

Abstract

... Volume: Page: Digital Object Identifier (DOI). ... Organic Letters. ... For the first time, rehydrated lyophilized cells were successfully used for the biohydroxylation. 3-Hydroxyazetidine and 4-hydroxypiperidine are useful pharmaceutical intermediates. ...

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Novel Analogues of Istaroxime, a Potent Inhibitor of Na+, K+...

[Gobbini, Mauro; Armaroli, Silvia; Banfi, Leonardo; Benicchio, Alessandra; Carzana, Giulio; Fedrizzi, Giorgio; Ferrari, Patrizia; Giacalone, Giuseppe; Giubileo, Michele; Marazzi, Giuseppe; Micheletti, Rosella; Moro, Barbara; Pozzi, Marco; Scotti, Piero Enrico; Torri, Marco; Cerri, Alberto Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4601 - 4608]