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Systematic synthesis of specifically 13C2H-labeled nucleosides from [ul-13 C 6]-d-glucose

AM Ono, T Shiina, A Ono, M Kainosho

Index: Ono, Akira Mei; Shiina, Toko; Ono, Akira; Kainosho, Masatsune Tetrahedron Letters, 1998 , vol. 39, # 18 p. 2793 - 2796

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Citation Number: 13

Abstract

A systematic approach, which combines previously reported reactions with appropriate modifications, was established for preparing a variety of selectively deuterated nucleosides from glucose. We have developed a systematic method of synthesizing specifically deuterated nucleosides from glucose. Selectively 13C 2H-doubly labeled nucleosides, such as [1′, 2′, 3′, 4′, 5′-13C5; 3′, 5′-2H2]-and [1′, 2′, 3′, 4′, 5′-13C5; 4′, 5′ ...