Use of 2, 3-bis (phenylsulfonyl)-1-propene as a multicoupling reagent

A Padwa, DN Kline, SS Murphree…

Index: Padwa, Albert; Kline, Donald N.; Murphree, S. Shaun; Yeske, Philip E. Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 298 - 306

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Citation Number: 24

Abstract

Once a monoadduct is formed, a new reactive site is present in the product. The introduction of an aminecontaining pendant functionality would provide an avenue for further chemical manipulation. One attractive subsequent reaction appeared to be the use of a suitable halide precursor for a radical ring closure. Cyclization reactions involving free-radical chain processes are rapidly gaining ground in the repertoire of synthetic In the construction of ...