Phosphorus, Sulfur, and Silicon

A Facile, Sequential Multicomponent Approach to N-Aminoamidinothioureas—Versatile Synthons to Bioactive Heterocycles

KG Sreejalekshmi

Index: Sreejalekshmi Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 9 p. 1830 - 1837

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Abstract

A sequential, three-component approach for the rapid and convenient one-pot synthesis of N-aminoamidinothioureas is reported. The improved synthetic strategy involves the selective blocking of amino functionality in aminoguanidine by Schiff base formation with carbonyl

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