Synthesis, characterization and cytotoxicity of platinum (II)/palladium (II) complexes with 1, 3-diaminopropane and 4-toluensulfonyl-L-amino acid dianion

J Zhang, L Ma, H Lu, Y Wang, S Li, S Wang…

Index: Zhang, Jinchao; Ma, Lili; Lu, Huiru; Wang, Yuechai; Li, Shenghui; Wang, Shuxiang; Zhou, Guoqiang European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 281 - 286

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Citation Number: 12

Abstract

Eight novel platinum (II)/palladium (II) complexes with 1, 3-dap and 4-toluensulfonyl-l-amino acid dianion,[Pt (1, 3-dap)(TsalaNO)]· 0.5 H2O (1a),[Pt (1, 3-dap)(TsvalNO)](1b),[Pt (1, 3- dap)(TspheNO)](1c),[Pt (1, 3-dap)(TsserNO)](1d),[Pd (1, 3-dap)(TsalaNO)]· 1.5 H2O (2a),[Pd (1, 3-dap)(TsvalNO)](2b),[Pd (1, 3-dap)(TspheNO)](2c) and [Pd (1, 3-dap)(TsileNO)](2d) have been synthesized and characterized by elemental analysis, IR, UV, 1H NMR and ...