A highly efficient carbon-sulfur bond formation reaction via microwave-assisted nucleophilic substitution of thiols to polychloroalkanes without a transition-metal …

…, H Cao, XN Xing, X Wang, WJ Xiao

Index: Cao, Yi-Ju; Lai, Yuan-Yuan; Cao, Hong; Xing, Xiao-Ning; Wang, Xiang; Xiao, Wen-Jing Canadian Journal of Chemistry, 2006 , vol. 84, # 11 p. 1529 - 1533

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Citation Number: 12

Abstract

An efficient carbon-sulfur bond formation reaction has been developed under microwave irradiation. This reaction affords a novel and rapid synthesis of thioacetals and sulfides under mild conditions. This method is particularly noteworthy given its experimental simplicity and high generality, and no transition-metal catalysts were needed under our conditions. Key words: microwave, sulfide, thiol, nucleophilic substitution.