Tetrahedron

Organocopper reagents in dimethyl sulfide11Part 15 of a series on New Copper Chemistry. For part 14 see Bertz, SH, Dabbagh, GJ Am. Chem. Soc. 1988, 110, 3668.

SH Bertz, G Dabbagh

Index: Bertz, Steven H.; Dabbagh, Gary Tetrahedron, 1989 , vol. 45, # 2 p. 425 - 434

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Citation Number: 74

Abstract

Organocopper (I) reagents, RCu, are both more stable and more reactive when prepared in dimethyl sulfide instead of ether or tetrahydrofuran. A wide range of Li reagents has been investigated with good results, as has a selection of Grignard reagents. Excellent yields of products are observed with typical substrates such as α, β-unsaturated ketones and acid chlorides.