New strong base synthesis of symmetrical 1, 5-diaryl-1, 3, 5-pentanetriones from acetone and benzoate esters

…, WT Pennington, DG VanDerveer

Index: Knight, John D.; Metz, Clyde R.; Beam, Charles F.; Pennington, William T.; VanDerveer, Donald G. Synthetic Communications, 2008 , vol. 38, # 14 p. 2465 - 2482

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Citation Number: 2

Abstract

Abstract Lithium hexamethyldisilazide (LiHMDS) was used to condense substituted benzoate esters with acetone to afford symmetrical 1, 5-diaryl-1, 3, 5-pentanetriones that were isolated, characterized (including a representative X-ray crystallographic analysis), and acid cyclized to the respective 2, 6-diaryl-4 H-pyran-4-ones.