A number of 3, kdisubstituted pyrazolo [3, 4-d] pyrimidine ribonucleosides were synthesized and tested for their biological activity. Glycosylation of persilylated as well as nonsilylated 3- bromoallopurinol with lO-acety1-2, 3, 5-tri-O-benzoyl-D-ribofuranose (4) provided the key intermediate 3-bromo-1-(2, 3, 5-tri-O-benzoyl-~-~-ribofuranosyl)-pyrazolo [3, 4-d] pyrimidin-4 (5H)-one (5a). Similar glycosylations of 3-cyanoallopurinol and 3-(methylthio) allopurinol ...
![1H-Pyrazolo[3,4-d]pyrimidine-3-carboximidamide,4,5-dihydro-4-oxo-1-b-D-ribofuranosyl-, monohydrochloride (9CI) Structure](https://image.chemsrc.com/caspic/387/90914-48-0.png)
![1H-Pyrazolo[3,4-d]pyrimidine-3-carbonitrile,4,5-dihydro-4-oxo- Structure](https://image.chemsrc.com/caspic/191/5387-84-8.png)
