A series of novel 12-(aryloxyacyloxyimino)-1, 15-pentadecanlactone derivatives (3) were synthesized, and their structures including configuration of C= N bond were confirmed by 1H NMR, elemental analysis and X-ray diffraction analysis. The bioassay showed that some of them exhibited excellent herbicidal activity against Amaranthus tricolor L. The activity of compounds 3 except compounds 3A1− 2 was much higher than the commercial herbicide ...