Synthesis

Synthesis of Exaltolide (Pentadecanolide) and Thioexaltolide from Cyclododecanone

JR Mahajan, HC De Araújo

Index: Mahajan, Jaswant Rai; Araujo, Hugo Clemente Synthesis, 1980 , # 1 p. 64 - 66

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Citation Number: 5

Abstract

The 16-membered lactone pentadecanolide, one of the fragrant components of angelica root oil and trivially named exaltolide “, figures among the first large-ring lactones synthesized over 50 years ago “. Due to its pleasant musk fragrance and strong fixative property, exaltolide is important in the perfumes and cosmetic-industry. Consequently, several syntheses of this macroeyclic lactone have been described”. The synthesis ...