Abstract Uracil, one of the four RNA bases is a vital component in the complex processes of molecular genetics. The correct functioning of these processes depends on the types of bonds formed by uracil with the surroundings. This communication elaborates the versatile potential of 1, 3-dimethyl-6-aminouracil (L 1) to form its 5-, 6-position substituted derivatives with different significant molecular packing behaviours. Presently, five crystals (L 2-L 6) ...