P2O5–SiO2 as an efficient heterogeneous catalyst for the solvent-free synthesis of 1-substituted 1H-1, 2, 3, 4-tetrazoles under conventional and ultrasound irradiation …

…, M Nasrollahzadeh, L Mehrabi, S Mostafaee

Index: Habibi, Davood; Nasrollahzadeh, Mahmoud; Mehrabi, Leila; Mostafaee, Samaneh Monatshefte fur Chemie, 2013 , vol. 144, # 5 p. 725 - 728

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Citation Number: 34

Abstract

Abstract 1-Substituted 1 H-1, 2, 3, 4-tetrazoles were efficiently synthesized from the reaction of primary amines, triethyl orthoformate, and sodium azide in presence of a catalytic amount of P 2 O 5–SiO 2 under conventional and ultrasound irradiation in solvent-free conditions. The advantages of this procedure are high yields, relatively short reaction times, ease of product isolation, low cost, and recovery and reusability of the catalyst. Graphical Abstract.