Tetrahedron letters

Regioselective schiff's base mediated deglycosidation of digitalis glycosides. New efficient synthesis of digoxigenin bis-digitoxoside and digoxigenin mono- …

M Adamczyk, J Grote

Index: Adamczyk, Maciej; Grote, Jonathan Tetrahedron Letters, 1995 , vol. 36, # 1 p. 63 - 66

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Citation Number: 6

Abstract

Dialdehydes derived from digoxin glycosides via sodium periodate oxidation were regioselectively deglycosylated by various amino acids in anhydrous methanolic solution to afford excellent yields of digoxigenin bis-digitoxoside and digoxigenin mono-digitoxoside in a single step.