Lipase-catalyzed aza-Michael reaction on acrylate derivatives

P Steunenberg, M Sijm, H Zuilhof…

Index: Journal of Organic Chemistry, , vol. 78, # 8 p. 3802 - 3813

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Citation Number: 15

Abstract

... The Journal of Organic ... J. Org ... The first example of a Michael addition in organic media catalyzed by enzymes was reported in 1988 by Kitazume et al.(14) Later, lipase-catalyzed Michael-type addition of various primary and secondary amines to acrylonitrile were reported.(15, 16 ...