Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents

M Yoshida, I Hayakawa, N Hayashi, T Agatsuma…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 14 p. 3328 - 3332

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Citation Number: 182

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... hit 1. In general, the nitro group in the structure of 1 is not preferred for drug design in medicinal chemistry on account ... The structural optimization of the right-hand region, Region 2, was carried out by parallel solution-phase chemistry. 5. ...