Tetrahedron letters

Halogenation of Pyridinols using Bis (sym-collidine) iodine (I) and Bis (sym-collidine) bromine (I) hexafluorophosphate

G Rousseau, S Robin

Index: Rousseau, Gerard; Robin, Sylvie Tetrahedron Letters, 1997 , vol. 38, # 14 p. 2467 - 2470

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Citation Number: 9

Abstract

We recently reported that the iodination of phenols occurred in excellent yields to iodophenols using bis(sym-collidine)iodine(I) hexafluorophosphate. [7]In these reactions all ortho-para free positions were substituted. We wondered if with pyridinols, the same comportment could be observed. The pyridinols used in this study were all commercially available. The halogenation reactions were carried out in methylene chloride at room temperature in the presence of ...