Synthesis of N-protected erythro-phenylalanylepoxides

…, G Raidaru, K Linask, J Järv, M Zetterström…

Index: Heinsoo; Raidaru; Linask; Jarv; Zetterstrom; Langel Tetrahedron Asymmetry, 1995 , vol. 6, # 9 p. 2245 - 2247

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Citation Number: 23

Abstract

N-et-Protected amino epoxides of general formula (6) are potential building blocks for synthesis of hydroxyethylene dipeptide isomers 1.2.3. These amino acid derivatives contain two stereogenic centers, which have been found to be important for their biological activity, but complicate chemical synthesis of these compounds. Stereoselective synthesis of erythro-isomers of several Cbz-N-et-protected ot - amino epoxides has been described recently 4. Supplementary to ...

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