Sodium Bis (trimethylsilyl) amide in the

JR Hwu, CH Hsu, FF Wong, CS Chung…

Index: Synthesis, , # 3 p. 329 - 332

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Citation Number: 13

Abstract

... Organic nitriles are traditionally synthesized from the cor- responding carboxylic acids by ultimate dehydration of the corresponding amide intermediates.3 The transforma- tions consist of two steps or more, and isolation of inter- mediates is required. ... 3; pp 617–620. ... SYNTHESIS ...

~26%

~83%

~87%

~92%

~60%

~22%

~55%

~23%

~85%

~59%

Highly efficient Beckmann rearrangement and dehydration of o...

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Transformation of aromatic bromides into aromatic nitriles v...

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Facile transformation of esters to nitriles

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Highly practical synthesis of nitriles and heterocycles from...

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Direct transformation of N, N-disubstituted amides and isopr...

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