Bulletin of the Chemical Society of Japan

Highly stereoselective palladium (0)-catalyzed allylation of active methylene compounds with allyl imidates under neutral conditions.

O Suzuki, S Inoue, K Sato

Index: Suzuki, Osamu; Inoue, Seiichi; Sato, Kikumasa Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 1 p. 239 - 243

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Citation Number: 7

Abstract

In the presence of a catalytic amount of Pd (0), active methylene compounds were allylated by allyl imidates under neutral conditions. In allylation with 3, 3-disubstituted allyl imidates, eg, geranyl and neryl imidate the effect of solvent and ligand to the E/Z ratio are investigated. The reaction in dimethyl sulfoxide by addition of diphosphine, eg, 1, 2-bis (diphenylphosphino) ethane, or large excess of triphenylphosphine as additive ligand ...