Tetrahedron

InCl 3 and In (OTf) 3 catalyzed reactions: synthesis of 3-acetyl indoles, bis-indolylmethane and indolylquinoline derivatives

R Nagarajan, PT Perumal

Index: Nagarajan, Rajagopal; Perumal, Paramasivan T Tetrahedron, 2002 , vol. 58, # 6 p. 1229 - 1232

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Citation Number: 214

Abstract

Indium trichloride and indium triflate were found to be effective catalysts for the acetylation of indoles to 3-acetyl indoles and is reported for the first time in good yield. Indium triflate is also found to be an efficient catalyst for the synthesis of bis-indolylmethane and indolylquinoline derivatives.

~94%

~70%

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