Model Studies on the Synthesis of Madangamine Alkaloids. Assembly of the Macrocyclic Rings

S Proto, M Amat, M Pérez, R Ballette, F Romagnoli…

Index: Proto, Stefano; Amat, Mercedes; Perez, Maria; Ballette, Roberto; Romagnoli, Federica; Mancinelli, Andrea; Bosch, Joan Organic Letters, 2012 , vol. 14, # 15 p. 3916 - 3919

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Citation Number: 9

Abstract

Using simplified model derivatives, the assembly of the macrocyclic rings of madangamines, including the 13-and 14-membered D rings of madangamines C–E, the all-cis-triunsaturated 15-membered D ring of madangamine A, and the (Z, Z)-unsaturated 11-membered E ring common to madangamines A–E, has been studied.