Tetrahedron

Facile synthesis of ethyl 2-arylpropenoates by cross-coupling reaction using electrogenerated highly reactive zinc

AA Jalil, N Kurono, M Tokuda

Index: Jalil, Aishah A; Kurono, Nobuhito; Tokuda, Masao Tetrahedron, 2002 , vol. 58, # 37 p. 7477 - 7484

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Citation Number: 47

Abstract

Highly reactive zinc metal was prepared by electrolysis of a DMF solution containing naphthalene and a supporting electrolyte in a one-compartment cell fitted with a platinum cathode and a zinc anode. This reactive zinc was used for efficient transformation of ethyl 2- bromoacrylate into the corresponding organozinc compound, which was reacted with various aryl iodides or bromides in the presence of 5mol% Pd (P (o-Tol) 3) 2Cl2 to give ...