New practical synthesis of indazoles via condensation of o-fluorobenzaldehydes and their o-methyloximes with hydrazine

K Lukin, MC Hsu, D Fernando…

Index: Journal of Organic Chemistry, , vol. 71, # 21 p. 8166 - 8172

Full Text: HTML

Citation Number: 74

Abstract

... The Journal of Organic Chemistry. ... Chicago, Illinois 60064. J. Org. Chem. , 2006, 71 (21), pp 8166–8172. DOI: 10.1021/jo0613784. Publication Date (Web): September 15, 2006. Copyright © 2006 American Chemical Society. ...

 Related Synthetic Route
2-Fluorobenzaldehyde Structure

446-52-6

2-Fluorobenzaldehyde

~44%

1H-Indazole Structure

271-44-3

1H-Indazole

2-Fluorotoluene Structure

95-52-3

2-Fluorotoluene

2-Bromo-6-fluorobenzaldehyde Structure

360575-28-6

2-Bromo-6-fluor...

~%

2-Bromo-6-fluorotoluene Structure

1422-54-4

2-Bromo-6-fluor...

2-bromo-6-fluorobenzaldehyde hydrazone Structure

914311-44-7

2-bromo-6-fluor...

~%

2-Bromo-6-fluorotoluene Structure

1422-54-4

2-Bromo-6-fluor...

4-Bromoindazole Structure

186407-74-9

4-Bromoindazole

2-Chloro-6-fluorobenzaldehyde Structure

387-45-1

2-Chloro-6-fluo...

~%

4-chloro-1H-indazol-3-amine Structure

20925-60-4

4-chloro-1H-ind...

2-Chloro-6-fluorobenzaldehyde Structure

387-45-1

2-Chloro-6-fluo...

~80%

2-Chloro-6-fluorotoluene Structure

443-83-4

2-Chloro-6-fluo...

4-Chloro-1H-indazole Structure

13096-96-3

4-Chloro-1H-indazole

2-fluoro-5-methoxybenzaldehyde Structure

105728-90-3

2-fluoro-5-meth...

~%

5-Methoxy-1H-indazole Structure

94444-96-9

5-Methoxy-1H-in...


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