A short, highly efficient synthesis of coenzyme Q10

…, P Mollard, SS Pfeiffer, W Chrisman

Index: Lipshutz, Bruce H.; Mollard, Paul; Pfeiffer, Steven S.; Chrisman, Will Journal of the American Chemical Society, 2002 , vol. 124, # 48 p. 14282 - 14283

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Citation Number: 108

Abstract

Open any textbook on basic biochemistry and there is likely to be considerable discussion devoted to the essential roles played by coenzyme Q 10 . 1 Its presence in virtually every cell in the human body accounts for its alternative name: ubiquinone. With close to three decades of biomedical science to its credit, the combination of a polar headgroup attached to a 50 carbon tail is a remarkable construct of evolution. Oftentimes referred to as the “miracle nutrient”, 2 CoQ 10 plays a ...