Asian Journal of Chemistry

Synthesis of New DOPA Derivative from L-Tyrosine for Construction of Bioactive Compound

D Sun, P Wan, G Zhang, M Luo

Index: Sun, Dequn; Wan, Peihong; Zhang, Guoqing; Luo, Min Asian Journal of Chemistry, 2013 , vol. 25, # 16 p. 9407 - 9408

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Abstract

A practical synthetic method of new DOPA derivative was developed with L-tyrosine as starting material. The new DOPA analogue could be used in building bioactive compounds. ... Key Words: Bioactive compound, L-DOPA analogue, Synthesis, L-Tyrosine. ... DOPA and its analogues have been useful unit in many biologically active natural products, such as the inhibitor of FPTase, pepticinnamin E1, OF4949-I2 (Fig. 1). ... 2/1 chloroform/methanol, reflux 4 h), ...