Dialkoxyphosphinyl-substituted enols of carboxamides

J Song, H Yamataka, Z Rappoport

Index: Song, Jinhua; Yamataka, Hiroshi; Rappoport, Zvi Journal of Organic Chemistry, 2007 , vol. 72, # 20 p. 7605 - 7624

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Citation Number: 8

Abstract

Reactions of isocyanates XNCO (eg, X= p-An, Ph, i-Pr) with (MeO) 2P (O) CH2CO2R [R= Me, CF3CH2,(CF3) 2CH] gave 15 formal “amides”(MeO) 2P (O) CH (CO2R) CONHX (6/7), and with (CF3CH2O) 2P (O) CH2CO2R [R= Me, CF3CH2] they gave eight analogous amide/enols 17/18. X-ray crystallography of two 6/7, R=(CF3) 2CH systems revealed Z-enols of amides structures (MeO) 2P (O) C (CO2CH (CF3) 2) C (OH) NHX 7 where the OH is cis ...