Convenient preparation of unsymmetrical 2, 5-disubstituted 1, 3, 4-oxadiazoles promoted by Dess–Martin reagent

…, CC Paraschivescu, I Dumitru, M Matache, I Baciu…

Index: Dobrota, Cristian; Paraschivescu, Codruta C.; Dumitru, Ioana; Matache, Mihaela; Baciu, Ion; Ruta, Lavinia L. Tetrahedron Letters, 2009 , vol. 50, # 17 p. 1886 - 1888

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Citation Number: 46

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 2,5-Disubstituted 1,3,4-oxadiazoles have been conveniently prepared by oxidative cyclization of N-acyl-N′-aryliden -hydrazines promoted by an excess of Dess–Martin periodinane under mild conditions (23 examples, up to 92% isolated yields). ... 2,5-Disubstituted 1,3,4-oxadiazoles have been ...

~71%

~53%

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