Use of the Graebe-Ullmann reaction in the synthesis of 8-methyl-γ-carboline and isomeric aromatic aza-γ-carbolines

RS Alekseev, AV Kurkin, MA Yurovskaya

Index: Alekseev; Kurkin; Yurovskaya Chemistry of Heterocyclic Compounds, 2012 , vol. 48, # 8 p. 1235 - 1250 Khim. Geterotsikl. Soedin., 2012 , vol. 48, # 8 p. 1235 - 1250,16

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Citation Number: 2

Abstract

Two variants of the Graebe-Ullmann reaction were used to obtain 8-methyl-5H-pyrido [4, 3- b] indole (8-methyl-γ-carboline) and the conditions for this reaction were optimized. The feasibility of using this method was studied for the synthesis of a series of isomeric aromatic