Tetrahedron

Expeditious synthesis of 1-substituted taurines with diverse functionalized side-chains

S Kakaei, N Chen, J Xu

Index: Kakaei, Saeed; Chen, Ning; Xu, Jiaxi Tetrahedron, 2013 , vol. 69, # 1 p. 302 - 309

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Citation Number: 14

Abstract

A radical addition reaction and subsequent performic acid oxidation were used for the synthesis of 1-substituted taurines with diverse functionalized side-chains from N- allylphthalimide and various xanthates. The current approach shows high yields and short synthetic route and reaction time. Moreover, the current method is a convenient and practical method for the synthesis of 1-substituted taurines with different functionalized side-chains.