Copper (II)-mediated autoxidation of tert-butylresorcinols

…, D Macikenas, JD Protasiewicz, LM Sayre

Index: Ling, Ke-Qing; Lee, Younghee; Macikenas, Dainius; Protasiewicz, John D.; Sayre, Lawrence M. Journal of Organic Chemistry, 2003 , vol. 68, # 4 p. 1358 - 1366

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Citation Number: 22

Abstract

Although copper (II)-mediated oxidation of phenols results in oxidative coupling rather than in oxygenation, it was recently reported that naturally occurring 5-alkylresorcinols undergo oxygenation in the presence of copper (II). To explore the generality of this reaction, the copper (II)-mediated autoxidation of 4-tert-butylresorcinol and 4, 6-di-tert-butylresorcinol was investigated and was found to result in direct oxygenation at open activated positions and, ...