New and Efficient Synthesis of Amides from Acid Chlorides Using Diisobutyl (amino) aluminum

JK Park, WK Shin, DK An

Index: Park, Jae Kyo; Shin, Won Kyu; An, Duk Keun Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 5 p. 1592 - 1594

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Citation Number: 2

Abstract

Amides are valuable functional groups in biological, agrochemical, and pharmaceutical molecules. 1 Several amides such as Weinreb amides, 2 morpholine amides, 3 and pyrrolidine amides 4 are useful intermediates for the synthesis of aldehydes or ketones. Among them, morpholine amides are a cheap and good substitute for Weinreb amides. A large number of synthetic methods for making amides from various carboxylic acid ...