Synlett

Deprotection of Tetrahydropyranyl Ethers with Montmorillonite K-10 Clay in Methanol

T Taniguchi, K Kadota, AS ElAzab, K Ogasawara

Index: Taniguchi, Takahiko; Kadota, Kohei; Elazab, Adel S.; Ogasawara, Kunio Synlett, 1999 , # 8 p. 1247 - 1248

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Citation Number: 9

Abstract

Abstract: A variety of tetrahydropyranyl (THP) ethers are removed by Montmorillonite K-10 clay in methanol at room temperature to give alcohols. It has been shown that the THP ethers carrying epoxy, methoxymethoxy (MOMO), tertbutyldiphenylsiloxy (TBDPSO-), acetoxy (AcO-) and benzoyloxy (BzO-) functionalities are stable under the conditions, while the ethers carrying ketal, tertbu-tyldimethylsioxy (TBSO-) and b, b, b-trichloroethylimidoxy [ ...