Tetrahedron

Palladium-catalyzed biaryl-coupling reaction of arylboronic acids in water using hydrophilic phosphine ligands

M Nishimura, M Ueda, N Miyaura

Index: Nishimura, Masato; Ueda, Masato; Miyaura, Norio Tetrahedron, 2002 , vol. 58, # 29 p. 5779 - 5787

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Citation Number: 95

Abstract

Hydrophilic phosphine ligands possessing a carbohydrate side-chain, such as N-(4- diphenylphosphinophenyl) methyl gluconamide (9), N-[4-(2′- dicyclohexylphosphinobiphenyl) phenylmethyl] gluconamide (10), and N-[4-(2′-di-t- butylphosphinobiphenyl)] phenylmethyl gluconamide (11), were newly synthesized to carry out palladium-catalyzed biaryl coupling of arylboronic acids in a single aqueous medium. ...