Chemistry–A European Journal

A Phosphane??Free Catalyst System for the Heck Arylation of Disubstituted Alkenes: Application to the Synthesis of Trisubstituted Olefins

C Gürtler, SL Buchwald

Index: Guertler, Christoph; Buchwald, Stephen L. Chemistry - A European Journal, 1999 , vol. 5, # 11 p. 3107 - 3112

Full Text: HTML

Citation Number: 167

Abstract

Abstract Trisubstituted olefins are easily accessible under mild reaction conditions using a new catalyst system consisting of dicyclohexylamine or methyl (dicyclohexyl) amine and a phase-transfer catalyst (see equation). The choice of the base was found to be crucial for the stereoselectivity and the rate of Heck type arylation reactions.