The Aminolysis of N-Nitrotoluenesulfonamides1

WD Emmons, JP Freeman

Index: Freeman et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 6062

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Citation Number: 3

Abstract

In connection with other investigations we have observed an extremely facile cleavage of the sulfonamide linkage. Substituted N-nitrotoluenesulfonamides are readily aminolyzed by secondary amines at room temperature to produce primary nitrarnines and the corresponding disubstituted tolucne amide. This reaction has proved to be a general