e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Organic letters
Synthesis of Spirotetramates via a Diels− Alder Approach
NA Butt, CJ Moody
Index: Moody, Christopher J.; Ward, John G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 12 p. 2903 - 2909
A study toward the unusual spirotetramate core of the pyrroindomycin antibiotics employing an intermolecular Diels− Alder reaction of an exo-methylene tetramic acid dienophile is described. The exo-methylene tetramate is readily synthesized from S-methylcysteine, and
