Potential precursors to chemically reactive species derived from the@-adrenergic antagonist propranolol were synthesized and tested for mutagenicity in the Ames Salmonella assay. N- Hydroxypropranolol (l), the corresponding aldonitrone, 34 l-naphthoxy)-2- hydroxypropionaldehyde N-isopropylnitrone (2), and N-nitrosopropranolol (3) were prepared and tested. N-Hydroxypropranolol (1) was obtained by direct alkylation of 3-(l- ...
![1-[hydroxy(propan-2-yl)amino]-3-naphthalen-1-yloxypropan-2-ol Structure](https://image.chemsrc.com/caspic/140/84418-31-5.png)