The Journal of Organic Chemistry

1, 1-Bis (dimethylamino)-2, 2, 2-trifluoroethane, a readily-available precursor to the novel fluorinated building block 1, 1-bis (dimethylamino)-2, 2-difluoroethene

Y Xu, WR Dolbier, XX Rong

Index: Xu, Yuelian; Dolbier Jr., William R.; Rong, Xiao X. Journal of Organic Chemistry, 1997 , vol. 62, # 6 p. 1576 - 1577

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Citation Number: 41

Abstract

Received January 3, 1997 In 1994, Aoyama reported in a Daikin patent the facile synthesis of 1,1,1,4,4,4-hexafluoro-2-butene (HFC-356mff) from the inexpensive hydrochlorofluorocarbon 1,1,1-tri- fluoro-2,2-dichloroethane (HCFC-123) by heating it at 60 °C with metallic copper in diethylamine.1 ... We reproduced that result, but found a small but significant impurity, CF3CH2Cl, which proved very dif- ficult to separate. In an attempt to further minimize this ...