1, 1, 2, 2-Tetrafluoroethyl-N, N-dimethylamine: a new selective fluorinating agent

…, S Swearingen, W Hong, WC Petersen

Index: Petrov; Swearingen; Hong; Chris Petersen Journal of Fluorine Chemistry, 2001 , vol. 109, # 1 p. 25 - 31

Full Text: HTML

Citation Number: 50

Abstract

The title compound has been prepared in 96–98% yield by the reaction of tetrafluoroethylene and dimethylamine. 1, 1, 2, 2-Tetrafluoroethyl-N, N-dimethylamine (1) is found to be an effective reagent for the conversion of alcohols into alkyl fluorides. Reaction of 1 and primary alcohols proceeds with high yield formation of the corresponding alkyl fluorides at elevated temperature. However, the reaction of secondary and tertiary ...