Mendeleev Communications

Synthesis of 4-haloquinolines and their fused polycyclic derivatives

MS Shvartsberg, EA Kolodina

Index: Shvartsberg, Mark S.; Kolodina, Ekaterina A. Mendeleev Communications, 2008 , vol. 18, # 2 p. 109 - 111

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Citation Number: 6

Abstract

A general method for the synthesis of 4-chloro-or 4-bromo-substituted quinolines and quinoline moieties of polycyclic compounds includes the addition of hydrogen halides to vic- amino (3-oxoalk-1-ynyl) arenes under mild conditions followed by the intramolecular cyclization of the adducts.