Synthesis

Synthesis of new cyclopropylisonitriles and their applications in Ugi four-component reactions

A Osipova, DS Yufit, A de Meijere

Index: Osipova, Anna; Yufit, Dmitrii S.; De Meijere, Armin Synthesis, 2007 , # 1 p. 131 - 139

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Citation Number: 7

Abstract

Abstract Several new cyclopropylisonitriles were synthesized from the corresponding cyclopropylamines (41-69% yield) and utilized in Ugi four-component reactions to furnish 12 new dipeptides in 38-86% yield. The structures of four of these dipeptides were determined by X-ray crystallography.