Tetrahedron

Recoverable silica-gel supported binam-prolinamides as organocatalysts for the enantioselective solvent-free intra-and intermolecular aldol reaction

A Bañón-Caballero, G Guillena, C Nájera, E Faggi…

Index: Banon-Caballero, Abraham; Guillena, Gabriela; Najera, Carmen; Faggi, Enrico; Sebastian, Rosa Maria; Vallribera, Adelina Tetrahedron, 2013 , vol. 69, # 4 p. 1307 - 1315

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Citation Number: 28

Abstract

Silica-gel supported binam-derived prolinamides are efficient organocatalysts for the direct intramolecular and intermolecular aldol reaction under solvent-free conditions using conventional magnetic stirring. These organocatalysts in combination with benzoic acid showed similar results to those obtained under similar homogeneous reaction conditions using an organocatalyst of related structure. For the intermolecular process, the aldol ...