Journal of the American Chemical Society

A Convenient Synthesis of Indole-3-acetic Acids1

MW Bullock, SW Fox

Index: Bullock; Fox Journal of the American Chemical Society, 1951 , vol. 73, p. 5155

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Citation Number: 20

Abstract

A convenient synthesis of indole-3-acetic acids frem ethyl y, y-dimethoxybutyrate and a phenylhydrazine or phenylhydrazine hydrochloride has been deseribed. By this procedure it is possible to prepare the intermediate ethyl succinaldehydate phenylhydrazone and to cyclize the intermediate to the corresponding indole-3-acetic acid in one operation. Several indole-3-acetie acids have been prepared by this method. The method has also been ...

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