The Journal of Organic Chemistry

The chemistry of 2'-amino analogs of 2'-hydroxychalcone and its derivatives

JA Donnelly, DF Farrell

Index: Donnelly, John A.; Farrell, David F. Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1757 - 1761

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Citation Number: 87

Abstract

In 1945, de Diesbach and Kramer'noted the similarity between 2-aryl-1, 2, 3, 4-tetrahydro-4- quinolones 1 and flavanones 3. Yet, except for the base-catalyzed isomerization of 2'- amino~ halcone~(2a) and its N-acetyl3 2b and N-tosyl'2c derivatives to the corresponding tetrahydro-4-quinolones la-c, little is of the potential of 2'-aminochalcone (2a) and its dihydro derivatives 4 to serve as precursors for 2-aryl-4-quinolones 1. These 2-arylsubstituted ...