Tetrahedron letters

Rapid and efficient synthesis of a fully functionalized synthon for the bottom half of the antiparasitic agent, ivermectin

ME Jung, Y Usui, CT Vu

Index: Jung, Michael E.; Usui, Yoshihiro; Vu, Chi Truc Tetrahedron Letters, 1987 , vol. 28, # 48 p. 5977 - 5980

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Citation Number: 35

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The preparation of the bottom half of ivermectin 3 in 10 steps and 9% overall yield is reported. ... Synthesis of a synthon for the bottom half of ivermectin with all the required functionality in the correct oxidation states, namely compounds 3, has been synthesized from 4 and 5 ...