Structure-Hypoglycemic Activity Relationships in 1-Naphthylalkylamines

G Pala, S Casadio, T Bruzzese…

Index: Pala,G. et al. Journal of Medicinal Chemistry, 1966 , vol. 9, p. 786 - 788

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Citation Number: 2

Abstract

In previous papers we reported hypoglycwiiic. sc+ recliiing results of many 1- naphthylalliylamiiie~. The cornpouilds possessed the general st rucxture 1, 111 which R was a hydrogen atom, or an alkyl or arninoall\-yI group; R'was a cyano. substituted or nnwbstitutecl carbamyl, free or esterified carboxy, carbureido, ketiiiiido, or keto group; SAd was a tertiary amino group; n= 2 or 3. During this investigation the most potent cwnpounda ...