Native DNA oligomers are shown to be stereoselective catalysts for the polymerization of 5'- amino-3'-acetaldehyde-modified thymidine/adenosine nucleosides through reductive amination. The reaction follows step-growth kinetics to read the encoded sequence and chain-length information in the antiparallel direction. Single mismatches in the template are selected against at a level of> 100: 1. A method is therefore established to translate ...
![1-[(2R,4S,5S)-5-(hydroxymethyl)-4-prop-2-enyloxolan-2-yl]-5-methylpyrimidine-2,4-dione Structure](https://image.chemsrc.com/caspic/295/120232-10-2.png)