Synthesis of Lipophilic Chemotherapeuticals. III. 1 Remarks on the Properties of Halogen-acylureas, Amides and Related Compounds

F Bergmann, L Haskelberg

Index: Bergmann; Haskelberg Journal of the American Chemical Society, 1941 , vol. 63, p. 1438

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Citation Number: 8

Abstract

Pearl and Dehn'recently reported the physical characteristics of the halogen-acetylureas. We have studied the toxicological and pharmacological properties of chlorinated acetylureas and related compounds, and in view of their general interest we should like to give a brief report of our results. From Table I it is evident that in the different series of compounds studied, the monochloroacetyl derivatives always show the greatest toxicity ...