Abstract A convenient synthetic approach to previously unknown NH imidoyl phosphonates, based on addition of dialkyl phosphites to trifluoroacetonitrile, has been developed. The synthetic potential of such imines, which exist as equilibrium mixtures of E/Z-isomers, was demonstrated by their easy reduction and functionalization with O-and P-centered nucleophiles, to afford derivatives of α-aminophosphonic acids containing a ...
